重组人IFNAR1蛋白-ACROBiosystems百普赛斯

Human IFN-alpha / beta R1 Protein, His Tag (MALS verified)

分子别名（Synonym）

IFNAR1,IFNAR,CRF2-1,IFN-R-1,IFNAR-1

表达区间及表达系统（Source）

Human IFN-alpha / beta R1 Protein, His Tag (IF1-H5225) is expressed from human 293 cells (HEK293). It contains AA Lys 28 - Lys 436 (Accession # P17181-1).

Predicted N-terminus: Lys 28

蛋白结构（Molecular Characterization）

This protein carries a polyhistidine tag at the C-terminus.

The protein has a calculated MW of 49.0 kDa. The protein migrates as 65-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

内毒素（Endotoxin）

Less than 1.0 EU per μg by the LAL method.

纯度（Purity）

>95% as determined by SDS-PAGE.

制剂（Formulation）

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

重构方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

-20°C to -70°C for 12 months in lyophilized state;

-70°C for 3 months under sterile conditions after reconstitution.

背景（Background）

干扰素α/β受体1（IFNAR1）也称为细胞因子受体II类成员1、细胞因子受体家族2成员1（CRF2-1）、I型干扰素受体1、IFNAR，属于II型细胞因子受体族。IFNAR1/IFNAR包含四个纤维连接蛋白III型结构域。IFNAR1与IFNAR2结合形成I型干扰素受体。IFNAR1是干扰素α和β的受体。IFNAR1可以在没有IFNAR2的帮助下转导IFNB信号，并且不会激活Jak-STAT通路。