（二氟甲基）三甲基硅烷 65864-64-4

CAS NO：65864-64-4

分子式(Molecular formula)：C4H10F2Si 

分子量(Molecular weight)：124.21

理化性质：沸点 52℃，相对密度 0.91g/cm3。

Physical and chemical properties: Boiling point 52 ℃, relative density 0.91g/cm3.

用途：

对烯醇化的芳香酮、脂肪酮，芳香醛、脂肪醛、双芳基酮、内酯等羰基化合物的亲核二氟甲基化，具有很好普适性。

在金属催化下(二氟甲基)三甲基硅烷参与偶联反应，如铜催化芳基碘或者烯基碘和(二氟甲基)三甲基硅烷的偶联反应。

作为二氟甲基源，合成一系列其他二氟甲基化试剂。

Purpose:

Nucleophilic difluoromethylation of enolizable aromatic ketones, aliphatic ketones, aromatic aldehydes, aliphatic aldehydes, diarylketones, lactones, and other carbonyl compounds under the presence of CsF/18-crown-6.

Under metal catalysis, (difluoromethyl) trimethylsilane participates in coupling reactions, such as copper catalyzed coupling reactions between aryl iodine or vinyl iodine and (difluoromethyl) trimethylsilane.

Difluoromethyl source of a series of other difluoromethylation reagents.