二氟甲基(2-吡啶基)砜，批次稳定性好、纯度高

产品名称：二氟甲基（2-吡啶基）砜

Product Name：Difluoromethyl (2-pyridyl) sulfone

别名：2-(二氟甲磺酰基)吡啶；2-(二氟甲烷磺酰基)吡啶；胡试剂；2-PySO₂CF₂H

Alias：2-(Difluoromethylsulfonyl)pyridine;2-[(Difluoromethyl)sulfonyl]pyridine; Difluoromethyl 2-pyridyl sulfone; Hu Reagent; 2-PySO₂CF₂H

CAS NO：1219454-89-3

分子式(Molecular formula)：C₆H₅F₂NO₂S

分子量(Molecular weight)：193.17

理化性质：熔点 48-50℃，沸点 324.4±42℃，相对密度 1.423±0.06 g/cm³，微溶于水，易溶于乙腈和甲醇。

Physical and chemical properties: melting point 48-50℃, boiling point 324.4±42℃， relative density 1.423±0.06 g/cm3 , slightly soluble in water, easily soluble in acetonitrile and methanol.

推荐用途：该试剂可用于二氟亚甲基引入，作为偕二氟烯基化试剂与醛和酮反应制备偕二氟烯烃；可用于二氟甲基引入，与芳基锌、芳基碘反应制备二氟甲基芳基化合物，与烯烃发生自由基加成反应；可以作为亲核二氟（磺化）甲基化试剂，用于从醛、酮、烷基卤代烃、三氟甲磺酸酯等合成α,α-二氟烷基亚磺酸盐以及磺酸盐；还可以与亲电碘化试剂和溴化试剂一起使用，用于一碘二氟甲基和一溴二氟甲基引入；还可以用作2-吡啶基化试剂。

Recommended use: This reagent can be used for the introduction of difluoromethylene, as a difluoroalkylation reagent to react with aldehydes and ketones to prepare difluoroalkenes; It can be used for the introduction of difluoromethyl, reacting with aryl zinc and aryl iodine to prepare difluoromethyl aryl compounds, and conducting free radical addition reactions with olefins; It can be used as a nucleophilic difluoro (sulfonation) methylation reagent for synthesis from aldehydes, ketones, alkyl halides, trifluoromethanesulfonic acid esters, etc α,α- Difluoroalkyl sulfinates and sulfonates; It can also be used together with electrophilic iodination reagents and bromination reagents for the introduction of monoiododifluoromethyl and monobromodifluoromethyl; It can also be used as a 2-pyridylation reagent.