重组人IL-21R蛋白-ACROBiosystems百普赛斯

Human IL-21R Protein, His Tag (MALS verified)

分子别名（Synonym）

IL21R,CD360,NILR

表达区间及表达系统（Source）

Human IL-21 R, His Tag (ILR-H5226) is expressed from human 293 cells (HEK293). It contains AA Cys 20 - Pro 236 (Accession # Q9HBE5-1).

Predicted N-terminus: Cys 20

蛋白结构（Molecular Characterization）

This protein carries a polyhistidine tag at the C-terminus.

The protein has a calculated MW of 26.9 kDa. The protein migrates as 37-47 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

内毒素（Endotoxin）

Less than 1.0 EU per μg by the LAL method.

纯度（Purity）

>90% as determined by SDS-PAGE.

>90% as determined by SEC-MALS.

制剂（Formulation）

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

重构方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

-20°C to -70°C for 12 months in lyophilized state;

-70°C for 3 months under sterile conditions after reconstitution.

背景（Background）

白细胞介素-21受体（IL21R）也称为CD抗原CD360，新型白细胞介蛋白受体（NILR），是白细胞介素-21的受体，属于I型细胞因子受体家族或4型亚家族。IL21R包含两个纤维连接蛋白III型结构域。IL21R在淋巴组织中选择性表达，在胸腺和脾脏中表达最高。IL21R转导IL21的促生长信号，对T细胞、B细胞和自然杀伤（NK）细胞的增殖和分化很重要。