胞渗透性多肽抑制剂多肽L-JNKI-1/胞渗透性多肽抑制剂多肽L-JNKI-1

Product Name：L-JNKI-1

CAS No.：N/A

Synonyms：胞渗透性多肽抑制剂多肽L-JNKI-1

Catalog No.：218P872

Brand：HongTide（上海鸿肽生物）

Description：L-JNKI-1是一种针对 JNK 的细胞渗透性多肽抑制剂多肽，是由31个氨基酸组成的多肽。在体内研究中，L-JNKI-1 已被证明可有效抑制 JNK 活性。 结果表明，Ang II 诱导剂量依赖性升压反应，JNK 抑制显着减弱了该反应。 还发现 10 μM L-JNKI-1 将磷酸化 c-Jun 降低 98%，磷酸化 Elk-1 降低 100%。 L-JNKI-1能够在腹腔注射后1小时内穿过血脑屏障并穿透成年小鼠和P5大鼠的神经元

L-JNKI-1 is a cell penetrating peptide inhibitor peptide targeting JNK, composed of 31 amino acids. In vivo studies have shown that L-JNKI-1 can effectively inhibit JNK activity. The results showed that Ang II induced a dose-dependent pressor response, and JNK inhibition significantly weakened this response. It was also found that 10 μ M L-JNKI-1 reduced phosphorylated c-Jun by 98% and phosphorylated Elk-1 by 100%. L-JNKI-1 can cross the blood-brain barrier and penetrate neurons in adult mice and P5 rats within 1 hour after intraperitoneal injection

Purity (HPLC) ≥98.0%

Single impurity≤2%

Peptide content≥75.0%

Amino Acid Composition≤±15%

Bacterial Endotoxins≤50EU/mg

Solubility：H₂O/DMSO

Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.

Storage:Cool dry place( Store at -20°C, away from the light)

Remark:For Research Use Only. Not for human use.

订购联系方式：

上海鸿肽生物科技有限公司

手机： +86-18018095145 （同微信号）

QQ: 3259098395

邮箱：sales1@hongtide.com

本产品仅供科研使用。