单克隆Anti C-MET抗体-ACROBiosystems百普赛斯

Recombinant Monoclonal Anti-C-MET Antibody, Rabbit (1A1)

描述/背景（Background）

MET is a tyrosine kinase receptor for the hepatocyte growth factor. It is linked to functions such as cell proliferation, scattering, morphogenesis, and survival. Ligand binding at the cell surface induces autophosphorylation of MET that provides docking sites for downstream signaling molecules. After activation of the ligand, MET interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, and STAT3. There interactions lead to the activation of signaling cascades including RAS-ERK, PI3, kinase-AKT, and PLCgamma-PKC. MET plays a role in embryonic development including gastrulation, development of muscles and neurons, angiogenesis, and kidney formation.

种属（Host Species）

Rabbit

克隆号（Clone）

1A1

适用方法（Application）

IHC

效价（Property）

1：1000

状态（State）

Liquid

阳性对照（Positive Control）

Human Placenta Tissue

克隆类型（Clonality）

Monoclonal

分子别名（Synonym）

C-MET

研究领域（Research Field）

Cancer Drug Targets

抗体来源（Source）

Rabbit

同种型（Isotype）

IgG

储存（Storage）

Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.