FGF19蛋白-ACROBiosystems百普赛斯

FGF19产品信息

英文名称：Fibroblast growth factor 19

中文名称：成纤维细胞因子19

靶点别称：FGF19

物种：Human

属性：Protein

标记：Unconjugated

内毒素（Endotoxin）

Less than 1.0 EU per μg by the LAL method.

纯度（Purity）

>95% as determined by SDS-PAGE.

制剂（Formulation）

Lyophilized from 0.22 μm filtered solution in PBS, 0.3 M NaCl, 0.3 M Arginine, pH7.4. Normally trehalose is added as protectant before lyophilization.

Contact us for customized product form or formulation.

重构方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

-20°C to -70°C for 12 months in lyophilized state;

-70°C for 3 months under sterile conditions after reconstitution.

FGF19分子背景

成纤维细胞生长因子（FGF）19是FGF新亚家族的第一个成员，可以作为激素。在胎儿期，FGF15/19参与器官发生，影响耳朵、眼睛、心脏和大脑的发育。FGFs-FGFR参与许多生物过程的调节，如胚胎发育、细胞增殖、分化和组织修复。在不同类型的疾病、障碍和癌症中观察到FGF-FGFR的失调。值得注意的是，FGF19/FGFR4的异常表达有助于肝细胞癌的进展。