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GP41蛋白-ACROBiosystems百普赛斯
产品详情:
- 中文名称:
- GP41蛋白
- 英文名称:
- GP41
- 品牌:
- 百普赛斯
- 产地:
- 北京
- 保存条件:
- -20°C to -70°C
- 纯度规格:
- 99.9%
- 产品类别:
- 重组蛋白
- 货号:
- GP41
- 用途范围:
- 药物开发等
- 规格:
- 100ug
- 是否进口:
- 否
GP41产品信息
英文名称:Transmembrane glycoprotein gp41
中文名称:跨膜糖蛋白gp41
靶点别称:HIV-1 (HXB2) GP41,GP41
物种:HIV-1 (HXB2)
属性:Protein
标记:Biotin-labeled/Unconjugated
内毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
纯度(Purity)
>85% as determined by SDS-PAGE.
制剂(Formulation)
Supplied as 0.2 μm filtered solution in 50 mM HEPES, 150 mM NaCl, pH7.5 with glycerol as protectant.
Contact us for customized product form or formulation.
运输(Shipping)
This product is supplied and shipped with dry ice, please inquire the shipping cost.
存储(Storage)
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
The product MUST be stored at -70°C or lower upon receipt;
-70°C for 3 months under sterile conditions.
GP41产品信息
Infection by HIV-1 involves the fusion of viral and cellular membranes with subsequent transfer of viral genetic material into the cell. The HIV-1 envelope glycoprotein that mediates fusion consists of the surface subunit gp120 and the transmembrane subunit gp41. gp120 directs virion attachment to the cell-surface receptors, and gp41 then promotes viral-cell membrane fusion. A soluble, alpha-helical, trimeric complex within gp41 composed of N-terminal and C-terminal extraviral segments has been proposed to represent the core of th e fusion-active conformation of the HIV-1 envelope. Three N-terminal helices within the bundle form a central, parallel, trimeric coiled coil, whereas three C-terminal helices pack in the reverse direction into three hydrophobic grooves on the surface of the N-terminal trimer. This thermostable subdomain displays the salient features of the core structure of the isolated gp41 subunit and thus provides a possible target for therapeutics designed selectively to block HIV-1 entry.
公司简介
成立日期 | (15年) |
注册资本 | 8000万人民币 |
员工人数 | 500人以上 |
年营业额 | ¥ 1亿以上 |
经营模式 | 工厂,试剂 |
主营行业 | 医药中间体,原料药,激素类,氨基糖苷类,中枢神经系统用药 |
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