FGF3/HBGF3蛋白-ACROBiosystems百普赛斯

FGF3产品信息

别称：FGF3,HBGF-3,Fibroblast growth factor 3

物种：Human

属性：Protein

标记：Unconjugated

内毒素（Endotoxin）

Less than 1.0 EU per μg by the LAL method.

纯度（Purity）

>95% as determined by SDS-PAGE.

制剂（Formulation）

Lyophilized from 0.22 μm filtered solution in 20 mM Mops,0.2 M Arginine,2 mM TCEP,2 mM EDTA, pH7.3 with trehalose as protectant.

Contact us for customized product form or formulation.

重构方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

-20°C to -70°C for 12 months in lyophilized state;

-70°C for 3 months under sterile conditions after reconstitution.

FGF3分子背景

成纤维细胞生长因子3（FGF3）属于成纤维细胞增长因子（FGF）家族，通过结合、二聚化和激活细胞表面FGF受体（FGFR）来调节多种发育过程，包括脑模式、分支形态发生和肢体发育。FGF/FGFR复合物已被证明在某些类型的癌症中起驱动致癌基因的作用，以细胞自主的方式维持肿瘤细胞的恶性特性。根据先前的研究，推测FGF3在癌症中上调，并加速肿瘤生长和血管生成。因此，FGF3被认为是癌症治疗的潜在靶点。