CD74重组蛋白-ACROBiosystems百普赛斯

CD74产品信息

英文名称：HLA-DR antigens-associated invariant chain

中文名称：HLA-DR抗原相关不变链

靶点别称：CD74,DHLAG,HLADG,II,Ia-GAMMA,p33,CLIP,INVG34

物种：Human

属性：Protein

标记：Unconjugated

内毒素（Endotoxin）

Less than 1.0 EU per μg by the LAL method.

纯度（Purity）

>95% as determined by SDS-PAGE.

制剂（Formulation）

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Contact us for customized product form or formulation.

重构方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

-20°C to -70°C for 12 months in lyophilized state;

-70°C for 3 months under sterile conditions after reconstitution.

CD74用户评价

CD74分子背景

分化簇74（CD74）也称为HLA II类组织相容性抗原γ链（HLADG）、DHLAG、Ia gamma、不变链（缩写II）。CD74/HLADG是一种参与MHC II类蛋白形成和运输的多肽。不变链的细胞表面形式被称为CD74。CD74在几种癌症中上调，并且在炎症期间也由非免疫细胞表达。CD74在MHC II类抗原加工中起着关键作用，它在复合物合成后不久就稳定了复合物中的无肽II类α/β异二聚体，并引导复合物从内质网运输到内体/溶酶体系统，在那里进行抗原加工和抗原肽与MHC II类的结合。CD74/DHLAG还充当细胞因子MIF的细胞表面受体。