GSK-3 beta重组蛋白-ACROBiosystems百普赛斯

GSK-3 beta产品信息

英文名称：Glycogen synthase kinase-3 beta

中文名称：糖原合酶激酶-3β

靶点别称：GSK3B,Glycogen synthase kinase-3 beta

物种：Human

属性：Protein

标记：Unconjugated

内毒素（Endotoxin）

Less than 1.0 EU per μg by the LAL method.

纯度（Purity）

>90% as determined by SDS-PAGE.

>90% as determined by SEC-HPLC.

制剂（Formulation）

Supplied as 0.2 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH7.5 with glycerol as protectant.

Contact us for customized product form or formulation.

运输（Shipping）

This product is supplied and shipped with dry ice, please inquire the shipping cost.

存储（Storage）

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

The product MUST be stored at -70°C or lower upon receipt;

-70°C for 3 months under sterile conditions.

GSK-3 beta分子背景

糖原合成酶激酶-3（GSK-3）是阿尔茨海默病（AD）发展过程中的关键分子。GSK-3β参与成对螺旋丝（PHF）-tau的形成，这是破坏神经元功能的神经原纤维缠结（NFT）沉积物的组成部分，也是AD神经退行性变的标志。