AXL受体酪氨酸激酶-ACROBiosystems百普赛斯

Axl产品信息

英文名称：AXL receptor tyrosine kinase

中文名称：AXL受体酪氨酸激酶

靶点别称：AXL,UFO

物种：Human/Cynomolgus

属性：Protein/Cell

标记：Biotin-labeled/Unconjugated

内毒素（Endotoxin）

Less than 1.0 EU per μg by the LAL method.

纯度（Purity）

>95% as determined by SDS-PAGE.

制剂（Formulation）

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Contact us for customized product form or formulation.

重构方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

-20°C to -70°C for 12 months in lyophilized state;

-70°C for 3 months under sterile conditions after reconstitution.

Axl分子背景

AXL受体酪氨酸激酶也称为酪氨酸蛋白激酶受体UFO，属于蛋白激酶超家族、Tyr蛋白激酶家族和AXL/UFO亚家族。AXL包含两个纤维连接蛋白III型结构域、两个Ig样C2型（免疫球蛋白样）结构域和一个蛋白激酶结构域。AXL在转移性结肠肿瘤中高度表达。AXL被GAS6结合和随后的自磷酸化激活。AXL通过结合生长因子参与从细胞外基质到细胞质的信号转导，从而参与细胞增殖的刺激。