aladdin 阿拉丁 N164060 N-羟基琥珀酰亚胺-PEG-N-羟基琥珀酰亚胺 MW 35 kDa

中文名：N-羟基琥珀酰亚胺-PEG-N-羟基琥珀酰亚胺

英文名：NHS-PEG-NHS

纯度：MW 35 kDa

货号：N164060

包装：100mg、500mg

存储温度：-20°C储存,充氩

产品介绍：

N-hydroxylsuccinimide (NHS) functionalized polyethylene glycol (PEG-NHS) is an amino (-NH₂) reactive PEG derivative that can be used to modify protein, peptide or any other surfaces with their available amino groups. NHS esters react with primary amine groups at pH 7~8.5 to form stable amide bonds.Compared to other PEG NHS ester derivatives, our succinimidyl carbonate (SC) functionalized mPEG-NHS offers superior reactivity and higher stability in aqueous solution. NHS esters react with deprotonated primary amines, therefore, the reaction requires neutral to basic pH values to proceed. Primary amines react with NHS esters by nucleophilic attack and NHS is released as a byproduct. Hydrolysis of the NHS-ester competes with the reaction in aqueous solution and increases with increasing pH.

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