aladdin 阿拉丁 M276110 甲氧基X04 863918-78-9 ≥97%

中文名：甲氧基X04

英文名：Methoxy-X04

中文别名：2,5-双(2-(4-羟苯基)乙烯基)茴香醚|4,4'-[(2-甲氧基-1,4-亚苯基)二- (1E)-2,1-亚乙基]双-苯酚

纯度：≥97%

货号：M276110

包装：25mg、5mg、1mg

Cas号：863918-78-9

存储温度：-20°C储存

产品介绍：

Description：

Methoxy-X04 is a brain-permeable fluorescent probe for amyloid-β (Aβ) to detect and quantify plaques, tangles, and cerebrovascular amyloid.1 It displays high in vitro binding affinity (Ki = 26.8 nM) for fibrillar β-sheet deposits and is used to image Aβ plaques in the brains of living APP/PS1 mice, a transgenic model of familial Alzheimer's disease.1,2 For in vivo imaging, APP/PS1 mice were injected with methoxy-X04 at a dose of 10 mg/kg, i.p., 24 hours prior to two-photon imaging.2 Methoxy-X04 displays an excitation peak at 750 nm with emission between 460 and 500 nm.2

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