aladdin 阿拉丁 C427222 白屈菜酸 99-32-1 10mM in DMSO

中文名：白屈菜酸

英文名：Chelidonic acid

中文别名：4-氧代-4H-吡喃-2,6-二甲酸|

英文别名：Chelidonic acid|99-32-1|4-OXO-4H-PYRAN-2,6-DICARBOXYLIC ACID|Jervaic acid|Jerva acid|Jervasic acid|Compound XI*|4-oxopyran-2,6-dicarboxylic acid|2,6-Dicarboxyl-4-pyrone|4H-Pyran-2,6-dicarboxylic acid, 4-oxo-|NSC 3979|Compound XI* (Cherry and Hageman)|4-Ox

纯度：10mM in DMSO

货号：C427222

包装：1ml

Cas号：99-32-1

存储温度：-80℃储存

产品介绍：

Chelidonic acid (CA) is a γ-pyrone. It is reported as constituent of the rhizome of Chelidonium majus L. It has many pharmacological effects, such as mild analgesic and antimicrobial effects. Therapeutic potential of CA for the treatment of intestinal inflammation has been investigated. CA is reported as inhibitor of the rat brain glutamate decarboxylase. Biosynthesis of CA in cell suspension cultures of Leucojum aestivum has been studied.

Biological activity

Chelidonic acid is a component of Chelidonium majus L., used as a mild analgesic, an antimicrobial, an acentral nervous system sedative. Chelidonic acid also shows anti-inflammatory activity. Chelidonic acid has potential to inhibit IL-6 production by blocking NF-κB and caspase-1. Chelidonic acid is a glutamate decarboxylase inhibitor, with a Ki of 1.2 μM。

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