aladdin 阿拉丁 T302268 他扎罗汀酸 118292-41-4 ≥98% (HPLC)

中文名：他扎罗汀酸

英文名：Tazarotenic acid

纯度：≥98%(HPLC)

货号：T302268

Cas号：118292-41-4

存储温度：2-8°C储存

运输条件：低温运输

产品介绍：

white to light brown powder

Biochemical/Physiological Effects：

Tazarotene is transformed to tazarotenic acid with the help of esterases. Tazarotenic acid regulates the pathogenic aspects of psoriasis through normalizing abnormal keratinocyte differentiation. It possesses strong anti-hyperproliferative effects in skin and reduces inflammation.

Tazarotenic acid, an active metabolite of tazarotene, is a potent and selective agonist of the retinoid receptor (RAR) that binds to RARα, RARβ, and RARγ. Tazarotenic acid relatively selective activates RARβ and RARγ. Tazarotenic acid is a first xenobiotic substrate of human retinoic acid hydroxylase CYP26A1 and CYP26B1.

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