aladdin 阿拉丁 C413847 Cyclo(-RGDfK) TFA 500577-51-5 99%

中文名：Cyclo(-RGDfK) TFA

英文名：Cyclo(-RGDfK) TFA

纯度：≥99%

货号：C413847

Cas号：500577-51-5

存储温度：-20°C储存

运输条件：超低温运输

产品介绍：

Information

Cyclo (-RGDfK) Cyclo (-RGDfK) is a potent and selective αvβ3 integrin inhibitor.

Targets

αvβ3 integrin

In vitro

The constant of affinity (K_D) of Cyclo (-RGDfK-) for purified integrin is 41.70 nM. Cyclo (-RGDfK) is reacting with HEK293(β3) cells moderately. Cyclo(-RGDfK-) modified micelles shows strong affinity to T-24 cells and strong inhibitory effect on the proliferation of T-24 cells.

In vivo

In athymic mice bearing α(v)β(3)-integrin-positive C6 gliomas, Cyclo (-RGDfK-) modification induces less tumor progression, less tumor metabolic activity, fewer intratumoral vessels.

Cell Research(from reference)

Cell lines：T-24 cells 

Incubation Time：72 h 

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