aladdin 阿拉丁 P413753 吡咯他汀（RR82）三氟乙酸盐 1472611-44-1 97%

中文名：吡咯他汀（RR82）三氟乙酸盐

英文名：Pyridostatin (RR82) Trifluoroacetate Salt

纯度：≥97%

货号：P413753

Cas号：1472611-44-1

存储温度：-20°C储存

运输条件：超低温运输

产品介绍：

Information

Pyridostatin (RR82) Trifluoroacetate Salt Pyridostatin Trifluoroacetate Salt (RR82) is a G-quadruplexe stabilizer with K d of 490 nM in a cell-free assay, which targets a series of proto-oncogenes.

Targets

G-quadruplexe (Cell-free assay) 490 nM(Kd)

In vitro

Pyridostatin decreases the proliferation of MRC-5–SV40 cells and various cancer cell lines, and induces cell-cycle arrest by DNA-damage checkpoint activation. Pyridostatin also reduces SRC-dependent cell motility in MDA-MB-231 cells by interacting with G-quadruplex motifs in SRC. Pyridostatin decreases EBNA1 synthesis via inhibition of G-quadruplexes.

Cell Research(from reference)

Cell lines：MRC-5–SV40 cells and various cancer cell lines 

Concentrations：10 μM 

Incubation Time：48 h 

查看阿拉丁官网此产品相关对应页面：https://www.aladdin-e.com/zh_cn/P413753.html