aladdin 阿拉丁 M414266 ME-401 1595129-71-7 98%

中文名：ME-401

英文名：ME-401

纯度：≥98%

货号：M414266

Cas号：1595129-71-7

存储温度：-20°C储存

运输条件：超低温运输

产品介绍：

Information

ME-401 (PWT-143, P110δ-IN-1) is an oral, potent and selective inhibitor ofPhosphatidylinositol 3-Kinase (PI3K) P110δwith IC50 of 0.6 nM in cellular assay.

Targets

P110δ (Cell-free assay) 0.6 nM

In vivo

ME-401 is an oral, once-daily, selective PI3Kδ inhibitor with an optimized pharmacologic profile that is in clinical development for the treatment of B-cell malignancies. ME-401 can be orally absorbed, distribute to target tissues, enter and accumulate in target cells, and bind to the target with high affinity to exert its mechanism of action.

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