aladdin 阿拉丁 A413296 阿莫奈韦 841301-32-4 98%

中文名：阿莫奈韦

英文名：Amenamevir

纯度：≥98%

货号：A413296

Cas号：841301-32-4

存储温度：-20°C储存

运输条件：超低温运输

产品介绍：

Information

Amenamevir Amenamevir (ASP2151) is a potent helicase-primase inhibitor and a novel class of antiviral agent.

Targets

helicase-primase

In vitro

ASP2151 inhibited the in vitro replication of HSV-1. The mean EC50s of ASP2151 against HSV-1 and HSV-2 were 14 (range, 7.7 to 20) and 30 ng/ml (range, 15 to 58), respectively.

In vivo

In the cutaneously HSV-1-infected mouse model, ASP2151 dose dependently suppressed intradermal HSV-1 growth, with the effect reaching a plateau at a dose of 30 mg/kg of body weight/day.

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