aladdin 阿拉丁 C413850 Cyclo(RGDyK) trifluoroacetate 250612-42-1 98%

中文名：Cyclo(RGDyK) trifluoroacetate

英文名：Cyclo(RGDyK) trifluoroacetate

纯度：≥98%

货号：C413850

Cas号：250612-42-1

存储温度：-20°C储存

运输条件：超低温运输

产品介绍：

Information

Cyclo(RGDyK) Cyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.

Targets

αVβ3 integrin 20 nM

In vitro

Cyclo(RGDyK) shows high affinity and selectivity for αVβ3 over αVβ5 and αIIbβ3. Cyclo(RGDyK)-conjugated micelles (TPM) facilitated the cell-specific uptake of DiI into B16-F10 cells and HUVECs via integrin-mediated endocytosis compared with Cyclo(RGDyK) -free micelles (NPM).

In vivo

In apoE−/− mice, Cyclo(RGDyK) (1 nmol, i.v.) inhibits the increase of αVβ3 integrin expression in the intima of the left stenotic carotid artery.

查看阿拉丁官网此产品相关对应页面：https://www.aladdin-e.com/zh_cn/C413850.html