aladdin 阿拉丁 P129711 盐酸帕罗西汀 半水合物 110429-35-1 ≥98% (HPLC)

中文名：盐酸帕罗西汀 半水合物

英文名：Paroxetine hydrochloride hemihydrate

中文别名：盐酸帕罗西汀半水合物

英文别名：Paroxetine hydrochloride hemihydrate|110429-35-1|Paxil|X2ELS050D8|Seroxat|Aropax|Paroxetine.HCl.hemihydrate|Paxil (TN)|(3S,4R)-3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-fluorophenyl)piperidin-1-ium;chloride|(3S,4R)-3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-fluo

纯度：≥98% (HPLC)

货号：P129711

包装：1g、5g

Cas号：110429-35-1

存储温度：2-8°C储存

产品介绍：

Paroxetine HCl, a phenylpiperidine derivative, is a highly potent and selective ST (serotonin transporter/5-HT) uptake inhibitor. It acts by binding to ST (serotonin transporter/SERT) with high affinity (Ki = 05 nM). In vitro paroxetine competitively inhibits the uptake of 5-HT by rat hypothalamic and cortical synaptosomes with only very weak inhibitory effects on SLC6A2 (noradrenaline) uptake and DAT (dopamine) uptake. Paroxetine HCl has also displayed a high affinity for muscarinic acetylcholine receptors. Other experiments have shown Paroxetine HCl to inhibit NOS (nitric oxide synthase) and also to be both a substrate and an inhibitor of CYP2D6 (cytochrome isoenzyme P450 2D6).A highly potent and selective serotonin (5-HT) uptake inhibitor

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