Siglec-15重组蛋白-ACROBiosystems百普赛斯

Siglec-15产品信息

英文名称：Sialic acid-binding Ig-like lectin 15

中文名称：唾液酸结合免疫球蛋白样凝集素-15

靶点别称：CD33 antigen-like 3,SIGLEC-15,CD33L3,sialic acid-binding Ig-like lectin 15,Siglec15,Siglec-15

物种：Human/Mouse/Cynomolgus

属性：Protein/Cell

标记：Biotin-labeled/Unconjugated

内毒素（Endotoxin）

Less than 1.0 EU per μg by the LAL method.

纯度（Purity）

>90% as determined by SDS-PAGE.

制剂（Formulation）

Lyophilized from 0.22 μm filtered solution in 25 mM MES, 150 mM NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

Contact us for customized product form or formulation.

重构方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

-20°C to -70°C for 24 months in lyophilized state;

-70°C for 12 months under sterile conditions after reconstitution.

Siglec-15用户评价

Siglec-15分子背景

Siglec-15是一种DAP12相关的免疫受体，属于免疫球蛋白超家族和Siglec（唾液酸结合Ig样凝集素）家族。Siglecs是结合唾液酸的细胞表面蛋白。它们主要存在于免疫细胞的表面，是I型凝集素的一个子集。Siglec-15由免疫球蛋白（Ig）样结构域、跨膜结构域和短细胞质尾部组成。Siglec-15识别唾液酸化聚糖并调节破骨细胞分化。Siglec-15是骨质疏松症的潜在治疗靶点，在脊椎动物的免疫系统中起着保守的调节作用。