CD133重组蛋白，ACROBiosystems百普赛斯

CD133产品信息

英文名称：CD133

中文名称：CD133抗原

靶点别称：CD133,PROM1,PROML1,Prominin-1,AC133

物种：Human

标签：His Tag

属性：Protein

标记：Unconjugated

内毒素（Endotoxin）

Less than 1.0 EU per μg by the LAL method.

纯度（Purity）

>90% as determined by SDS-PAGE.

制剂（Formulation）

This product is not suitable for cell based experiments due to cytotoxicity of DDM.

DDM and CHS are INDISPENSABLE to keep membrane protein soluble and active, under no circumastance should you remove DDM and CHS.

DDM/CHS buffer (DC-11) is sold separately and not included in protein, and please contact us if you need the buffer.

If glycerol is not compatible to your application, remove glycerol just before immediate experiment, and NEVER store glycerol-free protein solution.

Supplied as 0.2 μm filtered solution in 50 mM HEPES, 150 mM NaCl, DDM, CHS, pH7.5 with glycerol as protectant.

Contact us for customized product form or formulation.

运输（Shipping）

This product is supplied and shipped with dry ice, please inquire the shipping cost.

存储（Storage）

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

The product MUST be stored at -70°C or lower upon receipt;

-70°C for 3 months under sterile conditions.

CD133分子背景

Prominin-1也被称为CD133、抗原AC133、PROM1、PROML1和MSTP061。用作造血干细胞和祖细胞（HSPC）的标记，用于体干细胞分离。可能在细胞分化、增殖和凋亡中发挥作用。将胆固醇结合在含胆固醇的质膜微区中，并可能在上皮细胞顶端质膜的组织中发挥作用。在早期视网膜发育过程中，它是椎间盘形态发生的关键调节因子。参与MAPK和Akt信号通路的调控。在神经母细胞瘤中，细胞以RET依赖的方式抑制细胞分化，如神经突起的生长。

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