DNAM1重组蛋白，ACROBiosystems百普赛斯

DNAM1产品信息

物种：Human / Mouse / Cynomolgus / Canine

属性：Protein

标记：Biotin-labeled / Unconjugated

分子别名（Synonym）

DNAM1,CD226,PTA1

内毒素（Endotoxin）

Less than 1.0 EU per μg by the LAL method.

纯度（Purity）

>95% as determined by SDS-PAGE.

制剂（Formulation）

Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5 with trehalose as protectant.

Contact us for customized product form or formulation.

重构方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

1. -20°C to -70°C for 12 months in lyophilized state;

2. -70°C for 3 months under sterile conditions after reconstitution.

DNAM1分子背景

DNAX辅助分子1（DNAM-1）是一种单程I型膜蛋白，也被称为CD226抗原和血小板和T细胞活化抗原1（PTA1），其中含有2个Ig样C2型（免疫球蛋白样）结构域。DNAM-1是一种约65 kDa的糖蛋白，在自然杀伤细胞、血小板、单核细胞和T细胞亚群的表面表达。DNAM-1介导细胞与携带其配体CD112和CD155的其他细胞的粘附，并将DNAM-1与抗体交联导致细胞活化。此外，DNAM-1可以与PVR和PVRL2相互作用。