IFN-alpha/beta R2重组蛋白，ACROBiosystems百普赛斯

IFN-alpha/beta R2产品信息

物种：Human / Mouse / Rat

属性：Protein

标记：Unconjugated

分子别名（Synonym）

IFNAR2,IFNARB,IFNABR,IFN-R-2,IFN-alpha,beta receptor 2

内毒素（Endotoxin）

Less than 1.0 EU per μg by the LAL method.

纯度（Purity）

>95% as determined by SDS-PAGE.

制剂（Formulation）

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

重构方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

1. -20°C to -70°C for 12 months in lyophilized state;

2. -70°C for 3 months under sterile conditions after reconstitution.

IFN-alpha/beta R2分子背景

干扰素α/β受体2（IFNAR2）也称为IFNα结合蛋白、IFNα/β接收器2、I型干扰素受体2、IFNABR和IFNARB，后者是一种单程I型膜蛋白，属于II型细胞因子受体家族。IFNAR2可以与IFNAR1结合形成I型干扰素受体。IFNAR2是干扰素α和β的受体。IFNAR2参与IFN介导的STAT1、STAT2和STAT3激活。IFNAR2的异构体1和异构体2由于与TYR激酶JAK1的关联而直接参与信号转导。IFNAR2的异构体3是I型IFN受体活性的强效抑制剂。IFNAR2的遗传变异影响乙型肝炎病毒（HBV）感染的易感性。