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  • 血管生成素-2/ANG2蛋白,ACROBiosystems百普赛斯
  • 血管生成素-2/ANG2蛋白,ACROBiosystems百普赛斯
  • 血管生成素-2/ANG2蛋白,ACROBiosystems百普赛斯

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血管生成素-2/ANG2蛋白,ACROBiosystems百普赛斯

Angiopoietin-2
询价 100ug 起订
500ug 起订
1000ug 起订
北京 更新日期:2024-06-12

北京百普赛斯生物科技股份有限公司

VIP1年
联系人:姚经理
手机:18514007688 拨打
邮箱:jiaxin.zhao@acrobiosystems.com

产品详情:

中文名称:
血管生成素-2
英文名称:
Angiopoietin-2
品牌:
百普赛斯
产地:
北京
保存条件:
-20°C to -70°C
纯度规格:
99.9%
产品类别:
重组蛋白
货号:
Angiopoietin-2
用途范围:
药物开发等
规格:
ug
是否进口:

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Angiopoietin-2产品信息

英文名称Angiopoietin-2

中文名称:血管生成素-2

靶点别称ANGPT2,AGPT2,ANG2,Angiopoietin-2

物种:Human / Mouse / Rat / Rabbit

属性:Protein / Beads / Antibody Licensing

标记:Biotin-labeled / FITC Labeled / Unconjugated

内毒素(Endotoxin

Less than 1.0 EU per μg by the LAL method.

纯度(Purity

>95% as determined by SDS-PAGE.

制剂(Formulation

Lyophilized from 0.22 μm filtered solution in 20 mM MOPS, 150 mM NaCl, pH7.5 with trehalose as protectant.

Contact us for customized product form or formulation.

重构方法(Reconstitution

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储(Storage

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

1. -20°C to -70°C for 12 months in lyophilized state;

2. -70°C for 3 months under sterile conditions after reconstitution.

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Angiopoietin-2分子背景

Angiopoietin-2 is also known as ANGPT2, AGPT2, ANG2, and is a secreted glycoprotein that plays a complex role in angiogenesis and inflammation. Ang2 is widely expressed during development, but it is restricted postnatally to highly angiogenic tissues such as the placenta, ovaries, and uterus. It is particularly abundant in vascular endothelial cells (EC) where it is stored in intracellular Weibel Palade bodies. Both Ang2 and the related Angiopoietin1 (Ang1) are ligands for the receptor tyrosine kinase Tie 2. Ang2 functions as a proangiogenic factor, although it can also induce EC death and vessel regression. Upon its release from quiescent EC, it regulates vascular remodeling by promoting EC survival, proliferation, and migration and destabilizing the interaction between EC and perivascular cells. Ang2 is required for postnatal vascular remodeling, and it cooperates with Ang1 during lymphatic vessel development. It mediates the upregulation of ICAM1 and VCAM1 on EC, which facilitates the adhesion of leukocytes during inflammation. Ang2 competitively inhibit Ang1-induced endothelial cell responses mediated by Tie2, and reduces vascular integrity. But the role of Ang2 is controversial since the opposite outcomes has been reported in other studies. Over-expression of Ang2 disrupts the vascular remodeling, induce endothelial cell apoptosis, and may play an important regulating role in tumor angiogenesis. Ang2 also promotes the neuronal differentiation and migration of subventricular zone progenitor cells.

Angiopoietin-2用户评价

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Angiopoietin-2;血管生成素-2;ANG2蛋白;ANG2;ANGPT2;

公司简介

百普赛斯集团ACROBiosystems Group(股票代码:301080)是成立于2010年的跨国生物科技公司,是为全球生物医药、健康产业领域提供关键生物试剂产品及解决方案的行业平台型基石企业。2021年在创业板上市。百普赛斯集团业务遍布全球,横跨亚洲、北美洲、欧洲,在中国、美国、瑞士等12个城市设有办公室、研发中心及生产基地。目前累计服务客户超6000家,与全球Top 20医药企业均建立了长期、稳定的合作伙伴关系。集团旗下拥有品牌ACROBiosystems百普赛斯、bioSeedin柏思荟、Condense Capital垦拓资本和ACRODiagnostics百斯医学等。

成立日期 (14年)
注册资本 8000万人民币
员工人数 500人以上
年营业额 ¥ 1亿以上
经营模式 工厂,试剂
主营行业 医药中间体,原料药,激素类,氨基糖苷类,中枢神经系统用药

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