CD5重组蛋白，ACROBiosystems百普赛斯

CD5产品信息

英文名称：T-cell surface glycoprotein CD5

中文名称：T细胞表面糖蛋白CD5

靶点别称：CD5,LEU1

物种：Human / Mouse / Rabbit / Rhesus macaque

属性：Protein / Antibody

标记：Biotin-labeled / FITC Labeled / Unconjugated / PE Labeled

制剂（Formulation）

Lyophilized from 0.22 μm filtered solution in PBS, 0.5% BSA, pH7.4. Normally trehalose is added as protectant before lyophilization.

Contact us for customized product form or formulation.

重构方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please protect from light and avoid repeated freeze-thaw cycles.

This product is stable after storage at:

1. -20°C to -70°C for 12 months in lyophilized state;

2. -70°C for 3 months under sterile conditions after reconstitution.

CD5分子背景

T细胞表面糖蛋白CD5也称为淋巴细胞抗原T1/Leu-1和LEU1，在酪氨酸残基上被LYN磷酸化，因此CD5可以为PTPN6/SHP-1创造结合位点。CD5可能作为调节T细胞增殖的受体。CD5在人类B细胞的不同发育和激活阶段表达。CD5是TCR和BCR信号传导的公认负调控因子。CD5阳性细胞还可以通过提供细胞因子如IL-10来预防自身免疫的出现。不同B和T细胞亚群的发育、选择和功能或其优先存活可能直接或间接依赖于与CD5或CD5样分子相关的不同聚糖结构。

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