DcR3 / TNFRSF6B重组蛋白，ACROBiosystems百普赛斯

DcR3产品信息

别称：DcR3,TNFRSF6B

物种：Human

属性：Protein

标记：Unconjugated

内毒素（Endotoxin）

Less than 1.0 EU per μg by the LAL method.

纯度（Purity）

>90% as determined by SDS-PAGE.

制剂（Formulation）

Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5 with trehalose as protectant.

Contact us for customized product form or formulation.

重构方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

1. -20°C to -70°C for 12 months in lyophilized state;

2. -70°C for 3 months under sterile conditions after reconstitution.

DcR3分子背景

肿瘤坏死因子受体超家族成员6B（TNFRSF6B）也称为诱饵受体3（DcR3）、Fas配体诱饵受体和M68，属于肿瘤坏死因子接收器超家族。TNFRSF6是一种可溶性蛋白，含有四个TNFR-Cys重复序列。与TNFR超家族的大多数其他成员不同，TNFRSF6是一种不含跨膜结构域的可溶性蛋白。TNFRSF6B作为一种诱饵受体，与死亡受体竞争配体结合。该蛋白被认为在抑制FasL和LIGHT介导的细胞死亡和T细胞活化以及通过中和TL1A诱导血管生成方面发挥调节作用。