APRIL重组蛋白，ACROBiosystems百普赛斯

APRIL产品信息

英文名称：Tumor necrosis factor ligand superfamily member 13

中文名称：肿瘤坏死因子配体超家族成员13

靶点别称：APRIL,TNFSF13,TALL-2,TRDL-1,CD256,TALL2,ZTNF2

物种：Human / Cynomolgus

属性：Protein

标记：Biotin-labeled / Unconjugated

内毒素（Endotoxin）

Less than 1.0 EU per μg by the LAL method.

纯度（Purity）

>95% as determined by SDS-PAGE.

>90% as determined by SEC-MALS.

制剂（Formulation）

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

重构方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

1. -20°C to -70°C for 12 months in lyophilized state;

2. -70°C for 3 months under sterile conditions after reconstitution.

APRIL分子背景

APRIL（增殖诱导配体）也称为肿瘤坏死因子配体超家族成员13，TALL-2，TRDL-1，CD256，TNFFSF 13，与TNFRSF13B/TACI和TNFRSF17/BCMA结合的细胞因子。APRIL是主要与血液系统恶性肿瘤相关的肿瘤坏死因子家族的细胞因子。BAFF和APRIL都组装成同源三聚体，结合并激活它们部分共享的几种受体。不同化学计量比的BAFF-APRIL异聚体具有不同的受体结合特性和活性。此外，APRIL的表达受miR-145在GC细胞中的调节。

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