CD38重组蛋白，ACROBiosystems百普赛斯

CD38产品信息

英文名称：Lymphocyte differentiation antigen CD38

中文名称：淋巴细胞分化抗原CD38

靶点别称：CD38,T10,cADPr hydrolase 1

物种：Human / Mouse / Cynomolgus / Rabbit

属性：Protein / Antibody / Kits / Beads

标记：Biotin-labeled / FITC Labeled / Unconjugated

内毒素（Endotoxin）

Less than 1.0 EU per μg by the LAL method.

纯度（Purity）

>95% as determined by SDS-PAGE.

>95% as determined by SEC-MALS.

制剂（Formulation）

Lyophilized from 0.22 μm filtered solution in 50 mM MES, 100 mM NaCl, pH6.5 with trehalose as protectant.

Contact us for customized product form or formulation.

重构方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

1. -20°C to -70°C for 12 months in lyophilized state;

2. -70°C for 3 months under sterile conditions after reconstitution.

CD38分子背景

CD抗原CD38也被称为ADP核糖环化酶1，属于ADP核糖环化酶家族。CD38在胰腺、肝脏、肾脏、脑、睾丸、卵巢、胎盘、恶性淋巴瘤和神经母细胞瘤中高水平表达。CD38是一种多功能外酶，催化环状ADP核糖（cADPR）从NAD+合成和水解为ADP核糖。这些反应产物对于调节细胞内Ca2+至关重要。CD38功能的丧失与免疫反应受损、代谢紊乱和行为改变有关。CD38蛋白是细胞活化的标志物。它与艾滋病毒感染、白血病、骨髓瘤、实体瘤、II型糖尿病和骨代谢有关。CD38已被用作白血病的预后标志物。

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