CLEC12A重组蛋白，ACROBiosystems百普赛斯

CLEC12A产品信息

英文名称：C-Type lectin domain family 12 member A

中文名称：C型凝集素结构域家族12成员A

靶点别称：CLEC12A、MICL、CLL-1、CLL1、DCAL2、DCAL-2、CD371

物种：Human / Mouse / Cynomolgus / Rat

属性：Protein

标记：Biotin-labeled / FITC Labeled / Unconjugated / PE Labeled / APC Labeled

内毒素（Endotoxin）

Less than 1.0 EU per μg by the LAL method.

纯度（Purity）

>90% as determined by SDS-PAGE.

制剂（Formulation）

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

重构方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

1. -20°C to -70°C for 12 months in lyophilized state;

2. -70°C for 3 months under sterile conditions after reconstitution.

CLEC12A分子背景

CLEC12A（C型凝集素结构域家族12成员A）也称为CLL1、DCAL2、MICL。Clec12a是尿酸晶体的抑制性受体，在细胞死亡时调节炎症。调节信号级联并介导靶MAP激酶酪氨酸磷酸化的细胞表面受体。近年来，骨髓增生异常综合征（MDS）中出现了不同疾病增殖干细胞的证据。然而，CLEC12A在MDS中的作用仍有待阐明。此外，CLEC12A已被提出作为AML中白血病干细胞的有前景的标志物。

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