5'-Octyltocopherol (C8) CE-Phosphoramidite 新品

5'-Octyltocopherol (C8) CE-Phosphoramidite

Phosphoramidite used to incorporate a tocopherol modification at the 5' end of an oligonucleotide, with a C8 spacer.

Potential use in aiding cell delivery for nucleic acid therapeutics.

Includes a C8 spacer to minimise steric effects.

When used with a C6 S-S thiol, the tocopherol can be cleaved via the disulphide bridge, for example once the oligo has been delivered to the cell.

Has additional applications in the purification of ribozymes and thiol-modified oligos.