TSLP重组蛋白 ACROBiosystems百普赛斯

TSLP分子信息

英文名称：Thymic stromal lymphopoietin

中文名称：胸腺基质淋巴细胞生成素

靶点别称：TSLP

物种：Human / Mouse / Cynomolgus / Rat

属性：Protein

标记：Biotin-labeled / Unconjugated

内毒素（Endotoxin）

Less than 0.1 EU per μg by the LAL method.

无菌（Sterility）

The sterility testing was performed by membrane filtration method.

支原体（Mycoplasma）

Negative.

纯度（Purity）

>90% as determined by SDS-PAGE.

制剂（Formulation）

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

重构方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

1. -20°C to -70°C for 24 months in lyophilized state;

2. -70°C for 24 months under sterile conditions after reconstitution.

TSLP分子背景

胸腺基质淋巴生成素（TSLP）是一种上皮细胞衍生的细胞因子，参与炎症性皮肤病的病理过程，并在上皮细胞中广泛表达。人TSLP cDNA编码一个159个氨基酸（aa）残基的前体蛋白，其信号序列为28aa（4,5）。人类TSLP已被证明可以发展非破坏性中枢耐受，放大上皮诱导的类别转换，诱导特应性疾病，并维持肠道非炎症环境。在对人TSLP有反应的多种细胞中，CD11c+树突状细胞是特征最明显的靶细胞。

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