CD28蛋白/抗体 ACROBiosystems百普赛斯

CD28产品信息

英文名称：T-cell-specific surface glycoprotein CD28

中文名称：T细胞特异性表面糖蛋白CD28

靶点别称：CD28，CD28 Antigen，T-Cell-Specific Surface Glycoprotein CD28，CD28 Antigen (Tp44)，Tp44，CD28 Antigens，CD28 Molecule，T-Cell-Specific Surface Glycoprotein

物种：Human / Mouse / Cynomolgus / Rat

属性：Protein / Antibody / Kits / Antibody Licensing

标记：Biotin-labeled / Unconjugated

内毒素（Endotoxin）

Less than 1.0 EU per μg by the LAL method.

纯度（Purity）

>95% as determined by SDS-PAGE.

>90% as determined by SEC-MALS.

制剂（Formulation）

Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5 with trehalose as protectant.

Contact us for customized product form or formulation.

重构方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

1. -20°C to -70°C for 12 months in lyophilized state;

2. -70°C for 3 months under sterile conditions after reconstitution.

CD28分子背景

T细胞特异性表面糖蛋白CD28也称为TP44，是一种单程I型膜蛋白，含有一个Ig样V型（免疫球蛋白样）结构域。是T细胞上表达的提供T细胞活化所需的共刺激信号的分子之一。CD28是CD80（B7.1）和CD86（B7.2）的受体。当被Toll样受体配体激活时，CD80在抗原呈递细胞（APCs）中的表达上调。抗原呈递细胞上的CD86表达是组成型的。CD28是唯一在幼稚T细胞上组成型表达的B7受体。

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