间皮素（Mesothelin） ACROBiosystems百普赛斯

Mesothelin产品信息

英文名称：Mesothelin

中文名称：间皮素

靶点别称：MSLN，Mesothelin，MPF

物种：Human / Mouse / Cynomolgus / Rat

属性：Protein / Kits / Cell / Beads / Cell Grade Beads

标记：Biotin-labeled / Unconjugated

标记（Labeling）

Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.

蛋白标记度（Protein Ratio）

Passed as determined by the HABA assay / binding ELISA.

内毒素（Endotoxin）

Less than 0.01 EU per μg by the LAL method.

无菌（Sterility）

The sterility testing was performed by membrane filtration method.

支原体（Mycoplasma）

Negative.

纯度（Purity）

>95% as determined by SDS-PAGE.

制剂（Formulation）

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

重构方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

1. -20°C to -70°C for 12 months in lyophilized state;

2. -70°C for 3 months under sterile conditions after reconstitution.

Mesothelin背景

间皮素（MSLN）也被称为CAK1抗原，前巨核细胞增强因子，属于间皮素家族。间皮素/MSLN可以被弗林蛋白酶样转化酶蛋白水解切割成以下两条链：巨核细胞增强因子（MPF）和间皮素的切割形式。MPF和间皮素的裂解形式都是N-糖基化的。间皮素/MSLN可以与MUC16相互作用。膜锚定形式的MSLN可能在细胞粘附中发挥作用。MPF在体外增强巨核细胞集落形成。

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