aladdin 阿拉丁 E413568 E7046 (ER-886406) 1369489-71-3 99%

中文名：E7046 (ER-886406)

英文名：E7046 (ER-886406)

纯度：≥99%

货号：E413568

Cas号：1369489-71-3

存储温度：-20°C储存

运输条件：超低温运输

产品介绍：

Information

E7046 (ER-886406) E7046 (ER-886406) is a selective inhibitor of the prostaglandin E 2 (PGE 2 ) receptor EP4 with IC50 of 13.5 nM and Ki of 23.14 nM.

Targets

EP4 (Cell-free assay); EP4 (Cell-free assay) 13.5nM; 23.14 nM(Ki)

In vitro

E7046 has specific and potent inhibitory activity on PGE₂-mediated pro-tumor myeloid cell differentiation and activation.

In vivo

E7046 treatment reduces the growth or even rejected established tumors in vivo in a manner dependent on both myeloid and CD8⁺ T cells.

Cell Research(from reference)

Cell lines：Monocytes 

Concentrations：10,100,300,1000,or 3000 nM 

Incubation Time：7d 

查看阿拉丁官网此产品相关对应页面：https://www.aladdin-e.com/zh_cn/E413568.html