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网站主页 化工产品目录 生物化工 抑制剂 细胞周期(Cell Cycle) Chk 抑制剂 3-[(氨基羰基)氨基]-5-(3-氟苯基)-N-(3S)-3-哌啶基-2-噻吩羧胺 AZD776
  • AZD776

AZD776

5-(3-Fluorophenyl)-3-ureidothiophene-N-[(S)-piperidin-3-yl]-2-carboxamide
上海 更新日期:2020-12-17

上海化成医药化工有限公司

非会员
联系人:Mr Shi
电话:021-13621923966拨打
手机:13621923966 拨打
邮箱:chem88@sohu.com

产品详情:

中文名称:
AZD776
英文名称:
5-(3-Fluorophenyl)-3-ureidothiophene-N-[(S)-piperidin-3-yl]-2-carboxamide
CAS号:
860352-01-8

AZD7762 is a novel checkpoint kinase inhibitor with an IC50 of 5 and <10 nM for CHK1 and CHK2, respectively. It significantly prolonged the median time required for tumor volume doubling in response to gemcitabine and radiation. Together, findings suggest that G(2) checkpoint abrogation and homologous recombination repair inhibition both contribute to sensitization by Chk1 inhibition. Furthermore, they support the clinical use of AZD7762 in combination with gemcitabine and radiation for patients with locally advanced pancreatic cancer.

产品名称: AZD7762

CAS: 860352-01-8

包装:1g, 5g,10g,100g,1000g

含量:99%

上海化成医药化工有限公司

联系人:石先生

电话:13621923966

3-[(氨基羰基)氨基]-5-(3-氟苯基)-N-(3S)-3-哌啶基-2-噻吩羧胺

公司简介

Shanghai H&amp;C Chemical Co.,Ltd. is a innovative company engaged in organic intermediates, pharmaceutical ingredients, fine chemicals and custom synthesis. H&amp;C have high experience from lab to semiwork and commercial production,and manufacturing team have high experience in cost saving, process improvement and quality control. H&amp;C are high appraised by our customers for excellent quality and good price.

成立日期
注册资本
员工人数
年营业额
经营模式 工厂,定制,服务
主营行业 医药中间体,合成材料中间体,原料药,有机合成药,液晶中间体

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