aladdin 阿拉丁 D413067 去氢吴茱萸碱 67909-49-3 98%

中文名：去氢吴茱萸碱

英文名：Dehydroevodiamine

纯度：≥98%

货号：D413067

Cas号：67909-49-3

存储温度：-20°C储存

运输条件：超低温运输

产品介绍：

Information

Dehydroevodiamine (DHED), a constituent of Evodia rutaecarpa, has various biological effects such as hypotensive, negative chronotropic, ion channel depressant, inhibition of nitric oxide production and cerebral blood flow enhancing activities. Dehydroevodiamine inhibits LPS-induced iNOS, COX-2, prostaglandin E2 (PGE2) and nuclear factor-kappa B (NF-κB) expression in murine macrophage cells.

Targets

NF-κB ; COX-2 ; iNOS ; PGE2

In vivo

The dose ranging study demonstrated that the volume of distribution and clearance are independent of the dose. The primary route of elimination for the drug is via metabolism. i.v. administration of dehydroevodiamine elicited a slight but significant reduction in blood pressure and a marked decrease in heart rate.

Cell Research(from reference)

Cell lines：Cerebellar granule cells 

Concentrations：1-20 μM 

Incubation Time：9 days 

Product Describtion:

Dehydroevodiamine (DHED), a constituent of Evodia rutaecarpa, has various biological effects such as hypotensive, negative chronotropic, ion channel depressant, inhibition of nitric oxide production and cerebral blood flow enhancing activities. Dehydroevodiamine inhibits LPS-induced iNOS, COX-2, prostaglandin E2 (PGE2) and nuclear factor-kappa B (NF-κB) expression in murine macrophage cells.

查看阿拉丁官网此产品相关对应页面：https://www.aladdin-e.com/zh_cn/D413067.html