aladdin 阿拉丁 S288558 索纳哌唑 170858-33-0 ≥98%(HPLC)

中文名：索纳哌唑

英文名：Sonepiprazole

纯度：Moligand™，≥98%(HPLC)

货号：S288558

Cas号：170858-33-0

存储温度：2-8°C储存

运输条件：低温运输

产品介绍：

Product Describtion:

Sonepiprazole is a selective antagonist of the dopamine 4 (D4) receptor (Kis = 10 nM). It is highly selective over D1, D2, and D3 receptors, serotonin 1A and 2 receptors, as well as α1- and α2-adrenergic receptors (Kis > 2,000 nM). Its safety profile in rat studies is improved in comparison to classical antipsychotics but it is not effective for positive or negative symptoms of schizophrenia in patients. In a pharmacological model of stress exposure in rhesus monkeys, sonepiprazole reverses stress-induced cognitive deficits.

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