aladdin 阿拉丁 F303252 法匹拉韦 259793-96-9 ≥99%

中文名：法匹拉韦

英文名：Favipiravir (T-705)

纯度：Moligand™，10mM in DMSO

货号：F409106

Cas号：259793-96-9

存储温度：-80℃储存

运输条件：特低温运输

产品介绍：

Information

Favipiravir (T-705) is a potent and selectiveRNA-dependent RNA polymeraseinhibitor, used to treat influenza virus infections.
In vitro

Favipiravir shows anti-influenza virus activities with IC50 ranged from 0.013 to 0.48 μg/ml for the influenza A viruses, from 0.039 to 0.089 μg/ml for the influenza B viruses, and from 0.030 to 0.057 μg/ml for the influenza C viruses. In mammalian cell lines (MDCK cells, Vero cells, HEL cells, A549 cells, HeLa cells, and HEp-2 cells), Favipiravir shows no cytotoxicity at concentrations up to 1,000 μg/ml. In MDCK cells inoculated with seasonal influenza A (H1N1) viruses, Favipiravir induces lethal mutagenesis.

In vivo

In influenza virus-infected mice, Favipiravir (200 mg/kg/day, p.o.) protects the mice from death from influenza virus infection. In mice experimentally infected with Ebola virus, Favipiravir efficiently blocks viral production, reaching an antiviral effectiveness of 95% and 99.6% at 2 and 6days after initiation of treatment, respectively.
Cell Data

cell lines：

Concentrations：1000 μg/mL

Incubation Time：3 days

Powder Purity:≥99%

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