aladdin 阿拉丁 O102388 寡霉素A 来源于 淀粉酶产色链霉菌 579-13-5 ≥97%

中文名：寡霉素A 来源于 淀粉酶产色链霉菌

英文名：Oligomycin A from Streptomyces diastatochromogenes

中文别名：Oligomycin A;MCH 32

英文别名：MCH 32

纯度：≥97%

货号：O102388

包装：25mg、5mg

Cas号：579-13-5

存储温度：-20°C储存

产品介绍：

Oligomycin A inhibits ATP5 (mitochondrial ATPases, F1F0) bound to the cell membrane. This compound stimulates lysosome acidification due to shunting of membrane potential at a concentration of 1.5-3 μM. The compound has been observed to Induce apoptosis in a variety of cell types along with inducing a switch from the apoptotic to necrotic pathway. It also exhibits broad nematocidal, antifungal, and antitumor activities. Oligomycin A has caused dissipated mitochondrial membrane potential, decreased cytoplasmic ATP contents and disassembled metaphase II oocyte spindles when introduced to mouse oocytes.Oligomycin is used to inhibit membrane bount mitochondrial ATP synthase. It is used to inhibit sucrose synthesis and 14C translocation in sunflower leaves, to study antibiotic resistance, and to study carotid chemoreceptor responses to O2 and CO2 in the cat.

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