aladdin 阿拉丁 T124990 特立氟胺 163451-81-8 ≥99%

中文名：特立氟胺

英文名：Teriflunomide

中文别名：特立氟胺

英文别名：J-010046|MFCD00910058|HY-110159|NCGC00263218-07|A771726|A-771726|A77-1726|A801897|SW219377-1|2-Butenamide, 2-cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)-|2-cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)but-2-enamide|Aubagio|HMS3886K11|AC-521|IRINOTECAN H

纯度：≥99%

货号：T124990

包装：250mg、50mg

Cas号：163451-81-8

存储温度：2-8°C储存

产品介绍：

A77 1726, also known as teriflunomide, is the active metabolite of leflunomide. This compound has demonstrated antiinflammatory, antiproliferative, and immunosuppressive effects. A77 1726 has been shown to inhibit the proliferation of multiple mammalian cell lines in vitro, has demonstrated inhibition of Cox-2, dendritic cell function, DHODH (dihydroorotate dehydrogenase), and blocks TNF-dependent nuclear factor-κ B activation and gene expression. DHODH is an enzyme involved in the de novo synthesis of pyrimidine nucleotides, and its inhibition is thoμght to result in the antiproliferative effects on rapidly dividing cells, such as T-cells, observed by this compound.

查看阿拉丁官网此产品相关对应页面：https://www.aladdin-e.com/zh_cn/T124990.html