aladdin 阿拉丁 I424190 欧前胡素 482-44-0 10mM in DMSO

中文名：欧前胡素

英文名：Imperatorin

中文别名：前胡内酯|白芷乙素|前胡素|8-(3-甲基-2-丁烯氧基)补骨脂素|8-异戊烯氧基补骨脂素|白茅苷|9-[(3-甲基-2-丁烯-1-基)氧]-7H-呋喃并[3,2-g]色满-7-酮

英文别名：IMPERATORIN|482-44-0|Ammidin|Marmelosin|Pentosalen|8-Isoamylenoxypsoralen|8-Isopentenyloxypsoralene|Marmelide|NSC 402949|9-(3-methylbut-2-enoxy)furo[3,2-g]chromen-7-one|CCRIS 4346|HSDB 3497|9-(3-Methylbut-2-enyloxy)furo(3,2-g)chromen-7-one|EINECS 207-581-

纯度：10mM in DMSO

货号：I424190

包装：1ml

Cas号：482-44-0

存储温度：-80℃储存

产品介绍：

属呋喃香豆素类化合物。为棱柱状结晶（由乙醚）、长细针晶（由热水），易溶于氯仿，可溶于苯、乙醇、乙醚和苛性碱溶液，不溶于冷水。Imperatorin is a furocoumarin present in citrus fruits, which is used in HIV-1 research. Studies indicate that the transcription factor Sp1 is essential in the inhibitory functions of Imperatorin. In addition, Imperatorin inhibits cyclin D1 expression and stops the cell cycle at G1. These studies also suggest that Imperatorin suppresses HIV-1 replication in primary T lymphocytes and transformed cell lines. Furthermore, it has been suggested that the inhibitory effects of Imperatorin on HIV-1 at the transcriptional level can be monitored effectively in HeLa cells. Imperatorin can also cause apoptosis in human promyelocytic leukaemia, HL-60 via the cytochrome c/caspase-9 pathway.

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