aladdin 阿拉丁 H423879 1H-[1,2,4]恶二唑并[4,3-a]喹喔啉-1-酮 41443-28-1 10mM in DMSO

中文名：1H-[1,2,4]恶二唑并[4,3-a]喹喔啉-1-酮

英文名：1H-[1，2，4]Oxadiazolo[4，3-a]quinoxalin-1-one

纯度：Moligand™，10mM in DMSO

货号：H423879

Cas号：41443-28-1

存储温度：-80℃储存

运输条件：特低温运输

产品介绍：

ODQ is a selective and potent GCS (soluble guanylyl cyclase, sGC) inhibitor that binds competitively with nitric oxide. The GCS (sGC) serves as a receptor for nitric oxide, which is involved in the production of cyclic guanosine monophosphate (cGMP). In prostate cancer cell studies, ODQ induced caspase-3, enhanced cell death, and blocked cell migration. Inhibition of GCS (sGC) through ODQ results in blocking the actions of nitric oxide on vascular and platelet smooth muscle.

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