aladdin 阿拉丁 B101897 2-溴-4′-甲氧基苯乙酮 2632-13-5 98%

中文名：2-溴-4′-甲氧基苯乙酮

英文名：2-Bromo-4′-methoxyacetophenone

应用：A cell-permeable, covalent and potent protein tyrosine phosphatase inhibitor.

纯度：≥98%

货号：B101897

Cas号：2632-13-5

存储温度：2-8°C储存

运输条件：低温运输

产品介绍：

PTP inhibitor II is a cell-permeable, covalent and potent PTP (protein tyrosine phosphatase) inhibitor. The compound acts by binding the catalytic domain of the SH2 domain-containing phosphatase SHP-1(DSH2). PTP inhibitor II binds with lower affinity than PTP Inhibitor I (Ki = 128 μM and Ki = 43 μM respectively). The inhibition can be reversed by irradiation of the inactivated PTP at 350 nm. PTP inhibitors have demonstrated enhanced clonogenic survival, mutagenesis and cell growth. PTP inhibitors can also be useful for probing signal transduction pathways as well as drμgs for treatment of PTP-related diseases. PTP Inhibitor II is an inhibitor of PTP1B and SH-PTP1.A cell-permeable, covalent and potent protein tyrosine phosphatase inhibitor.

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