aladdin 阿拉丁 A102398 艾菲地可宁 38966-21-1 98%

中文名：艾菲地可宁

英文名：Aphidicolin

英文别名：aphidicolin|38966-21-1|(+)-Aphidicolin|(+/-)-Aphidicolin|ICI 69653|NSC-234714|Aphidicolin, (+/-)-|(3R,4R,4aR,6aS,8R,9R,11aS,11bS)-4,9-bis(hydroxymethyl)-4,11b-dimethyltetradecahydro-8,11a-methanocyclohepta[a]naphthalene-3,9-diol|NSC234714|6B3F8QW8TU|CHEMB

纯度：98%

货号：A102398

包装：10mg、1mg、5mg

Cas号：38966-21-1

存储温度：2-8°C储存

产品介绍：

Aphidicolin is a tetracyclic diterpene antibiotic and DNA synthesis inhibitor isolated from Cephalosporium aphidicola. Aphidicolin is reported to specifically inhibit DNA polymerase α and δ via binding to the enzyme, in eukaryotic cells such as the HeLa cell line, without affecting other DNA polymerases. This compound blocks the cell cycle at early S phase and has been reported to be useful for synchronizing cell cycles in cultured eukaryotic cells. This compound is also noted to induce apoptosis in HeLa S3 cells after 18-24 hours of the cell cycle.A novel tetracyclic diterpene antibiotic and also a DNA synthesis inhibitor in eukaryotes

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