GW1929 Calbiochem,196808-24-9

别名

GW1929 - CAS 196808-24-9 - Calbiochem,PPAR Agonist V, PPARγ Agonist IV

一般描述

A potent, tyrosine-based peroxisome proliferator-activated receptor γ (PPARγ) agonist (EC50 = 13 nM for murine PPARγ and 6.2 nM for human PPARγ in cell-based transactivation assays). A potent, tyrosine-based peroxisome proliferator-activated receptor γ (PPARγ) agonist (EC50 = 13 nM for murine receptor and 6.2 nM for human receptor in cell-based transactivation assays).

生化/生理作用

Cell permeable: no EC50 = 13 nM as peroxisome proliferator-activated receptor γ (PPARγ) agonist for murine receptor and 6.2 nM for human receptor in cell-based transactivation assays Primary Target
Peroxisome proliferator-activated receptor γ (PPARγ) agonist Product does not compete with ATP. Reversible: no

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

其他说明

Han, S., et al. 2004. Clin. Cancer Res.10, 1911.
Willson, T.M., et al. 2000. J. Med. Chem.43, 527.
Brown, K.K., et al. 1999. Diabetes48, 1415.