溴芬酸钠水合物 120638-55-3

Bromfenac sodium hydrate
120638-55-3

询价 500G 起订

1000G 起订

5000G 起订

江西更新日期：2024-07-05

江西瑞威尔生物科技有限公司

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产品详情:

中文名称：: 溴芬酸钠水合物

英文名称：: Bromfenac sodium hydrate

CAS号：: 120638-55-3

品牌：: 瑞威尔

产地：: 江西

保存条件：: 常温密封储存

纯度规格：: ≥98%

产品类别：: API&医药中间体

CAS编号：: 120638-55-3

EINECS编号：: 695-342-6

别名：: 溴芬酸钠

分子式：: C15H11BrNNaO3

含量纯度：: ≥98%

产地/厂商：: 江西瑞威尔生物

英文名称：: Bromfenac sodium hydrate

性状：: 白色粉沫结晶

储藏：: 室内常温密封储存

单杂：: ≤0.1%

质量标准：: 企业内控标准

120638-55-3

溴芬酸钠(Bromfenac sodium)

CAS: 91714-93-1;120638-55-3

化学式: C15H11BrNNaO3

120638-55-3 - 基本信息

中文名	溴芬酸钠
英文名	Bromfenac sodium
别名	溴芬酸钠溴酚酸钠溴芬那酸钠溴芬酸钠水合物溴芬那酸钠水合物溴芬酸钠120638-55-3 (2-氨基-3-(4-溴苯甲酰)苯基)乙酸钠 [2-氨基-3-(4-溴苯甲酰基)苯基]乙酸钠 (2-氨基-3-(4-溴苯甲酰)苯基)乙酸钠水合物
英文别名	Duract Unii-8ecv571Y37 Bromfenac sodium Bromfenac ophthalmic Bromfenac ophthalmic solution Bromfenac Sodium Sesquihydrate Bromfenac monosodium salt sesquihydrate [2-amino-3-(4-bromobenzoyl)phenyl]acetic acid Sodium (2-amino-3-(4-bromobenzoyl)phenyl)acetate Sodium [2-amino-3-(4-bromobenzoyl)phenyl]acetate 2-Amino-3-(4-bromobenzoyl)phenylacetic acid sodium salt Sodium 2-amino-3-(4-bromobenzoyl) phenylacetate sesquihydrate sodium {2-amino-3-[(4-bromophenyl)carbonyl]phenyl}acetate hydrate
CAS	91714-93-1 120638-55-3
EINECS	695-342-6
化学式	C15H11BrNNaO3
分子量	356.15
InChI	InChI=1/C15H12BrNO3.Na.H2O/c16-11-6-4-9(5-7-11)15(20)12-3-1-2-10(14(12)17)8-13(18)19;;/h1-7H,8,17H2,(H,18,19);;1H2/q;+1;/p-1
熔点	268-270°C (dec.)
沸点	562.2°C at 760 mmHg
闪点	293.8°C
蒸汽压	1.77E-13mmHg at 25°C
存储条件	Refrigerator
体外研究	Bromfenac (90 μg/mL; 48 h) inhibits TGF-b1-induced extracellular matrix (ECM) synthesis and myoﬁbroblast activation in HConFs and HPFs. Bromfenac (30-90 μg/mL; 48 h) decreases the protein and mRNA expression levels of FN, COL3, a-SMA, and survivin in a dose-dependent manner in HConFs and HPFs. Bromfenac (30-90 μg/mL; 48 h) declines the phosphorylated protein levels of AKT, ERK1/2, and GSK-3b-S9 with dosage in HPFs and HConFs.
体内研究	Bromfenac (0.0032-3.16%; 100 or 200 μL; rubbed onto the backs) produces significant anti-inflammatory activity at concentrations as low as 0.1% (4 h pretreatment time) or 0.32% (18h pretreatment time) in rats. Bromfenac (0.032-3.16%; 100 μL; rubbed onto the paws) produces dose-related anti-inflammatory activity in rats. Bromfenac (0.032-1.0%; 50 μL) is 26 times more potent than indomethacin in blocking the erythema when applied directly onto the skin area exposed to UV light in guinea pigs. Bromfenac (0.0032-0.1%; 50μL; rubbed onto the uninjected paw for 4 h per day and 5 days per week) produces a dose and time dependent reduction in the paw volume of both hind limbs in rats. Bromfenac (0.32%; 50μL; rubbed onto the abdomen) produces significant blockade of abdominal constriction to ACh challenge in mice. Animal Model: Male Sprague-Dawley rats (150-250 g) are injected carrageenan Dosage: 0.0032, 0.01, 0.032, 0.1, 0.32, 1.0, 3.16% (100 or 200 μL) Administration: Rubbed onto the backs before 1-72 h of injected carrageenan Result: Produced significant anti-inflammatory activity when applied 1, 2, and 4 h prior to carrageenan challenge at 0.32%. Applied 1 or 4 h prior to carrageenan challenge was active, but not when applied 24 h (or longer) prior to challenge at 0.2%.

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溴芬酸钠眼药工厂;溴芬酸钠水合物检测方法;溴芬酸钠环评公示;溴芬酸钠出口;

瑞威尔依托峡江医药大健康产业基础，初步形成了生产加工中成药、原料药、医药中间体、保健药、兽药、医疗器械等产品的产业发展格局，大力推进医药化工产业基地建设。瑞威尔专业从事生物医学技术服务、技术咨询及产品开发的生物技术服务企业。公司致力于以生物科技、医药科技的技术开发、技术咨询；以及医药中间体、化工产品及化工原料（不含危化品）的研发、销售；其中包括化妆品原料、食品添加剂、饲料添加剂、兽药、农药、香精香料、医药原料、化工原料等产品技术为核心的生产、研发；还包括货物的进出口、技术的进出口。

成立日期	(4年)
注册资本	200万
员工人数	1-10人
年营业额	￥ 100万以内
经营模式	贸易,工厂,试剂,定制,服务
主营行业	化学农药原药,中间体,化学试剂,医药原料,日用化工