N-甲氧琥珀酰基-丙氨酰-丙氨酰-脯氨酰-缬氨酸-7-氨基-4-甲基香豆素/72252-90-5/MeOSuc-Ala-Ala-Pro-Val-AMC

Product Name：MeOSuc-Ala-Ala-Pro-Val-AMC

CAS No.：72252-90-5

Synonyms：甲氧基琥珀酰 (MeO-Suc) 肽 AAPV

Catalog No.：140P197

Brand：HongTide（上海鸿肽生物）

Description：MeOSuc-Ala-Ala-Pro-Val-AMC是人类白细胞和猪胰弹性蛋白酶的荧光底物多肽，序列中含有3个氨基酸。MeOSuc-Ala-Ala-Pro-Val-AMC会被这些弹性蛋白酶快速水解，但不会被组织蛋白酶 G 水解。添加 7-氨基-4-甲基香豆素 (AMC) 会生成低荧光肽（激发：355-380 nm；发射 440-460 nm)，表明在弹性蛋白酶存在下荧光呈线性增加。 这种肽基-AMC 底物可检测低至 11 pM 的人类白细胞弹性蛋白酶和 18 pM 的猪胰腺弹性蛋白酶。

MeOSuc-Ala-Ala-Pro-Val-AMC is a fluorescent substrate peptide of human leukocytes and porcine pancreatic elastase, with a sequence containing three amino acids. MeOSuc-Ala-Ala-Pro-Val-AMC is rapidly hydrolyzed by these elastases, but not by cathepsin G. Adding 7-amino-4-methylcoumarin (AMC) generates low fluorescence peptides (excitation: 355-380 nm; emission: 440-460 nm), indicating a linear increase in fluorescence in the presence of elastase. This peptide based AMC substrate can detect human leukocyte elastase as low as 11 pM and porcine pancreatic elastase as low as 18 pM.

Purity (HPLC) ≥98.0%

Single impurity≤2%

Peptide content≥75.0%

Amino Acid Composition≤±15%

Bacterial Endotoxins≤50EU/mg

Solubility：H₂O/DMSO

Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.

Storage:Cool dry place( Store at -20°C, away from the light)

Remark:For Research Use Only. Not for human use.

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